Search Dictionary
Definition of horsepox
horsepox
/ˈhɔːrsˌpɑːks/
horse · pox
horsepox Lexical Profile
CEFR
C2
Grade
11
Tier
3
Usage
Rare
horsepox Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
A rare or possibly extinct viral disease of horses, caused by an orthopoxvirus, characterized by fever and the eruption of pustules on the skin and mucous membranes.
Example
"Historical medical records suggest that horsepox was once widespread in Europe and may have played a crucial role in the early development of the smallpox vaccine."
• Nearby Words
Word Origin & Etymology
A compound of 'horse' and 'pox' (an alteration of 'pocks', referring to pustules). It holds historical significance in immunology, as Edward Jenner believed that the cowpox used for his first smallpox vaccines originally derived from this equine disease.
Cite this Entry
Wordmom. (2026). Definition of Horsepox. In Wordmom Dictionary. Retrieved Oct 16, 2026, from https://wordmom.com/dictionary/horsepox