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Definition of degenerative

degenerative

/dɪˈdʒɛn.ə.rə.tɪv/
de · gen · er · a · tive

Adverb:degeneratively
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degenerative Lexical Profile

degenerative Game Scores & Validity

• adjective

1

Of a disease or physical condition, characterized by progressive, often irreversible deterioration and loss of function in the organs, tissues, or cells.

Example

"Researchers are testing a promising new therapy designed to slow the progression of degenerative neurological disorders."


2

Tending to decline, worsen, or cause a gradual loss of quality, structure, or vitality.

Example

"Prolonged neglect and lack of investment had a degenerative effect on the city's public transit infrastructure."

Synonyms
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Antonyms
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Word Nuance & Usage

Do not confuse 'degenerative' with 'degenerate'. 'Degenerative' is strictly used in clinical, biological, or formal analytical contexts to describe a progressive physical or structural decline (e.g., 'a degenerative joint condition'), whereas 'degenerate' as an adjective carries strong moral or social condemnation.

• Rhymes for degenerative

Word Origin & Etymology

Formed in the mid-19th century from the verb 'degenerate' plus the suffix '-ive', tracing back to the Latin 'degeneratus', meaning 'fallen from one's ancestral quality or race'.

Cite this Entry


Wordmom. (2026). Definition of Degenerative. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/degenerative
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