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Definition of degeneration
degeneration
/dɪˌdʒɛn.əˈreɪ.ʃən/
de · gen · er · a · tion
Adverb:degeneratively
•Plural:degenerations
•Adjective:degenerative
degeneration Lexical Profile
CEFR
C1
Grade
10
Tier
2
Usage
Top 10k
Syllables
5
degeneration Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
The progressive deterioration of tissues, cells, or organs in which they lose their specialized structure and function due to disease, injury, or aging.
Example
"Early detection can help slow the progression of age-related macular degeneration."
2
The state or process of declining in quality, standard, or moral character; a worsening or falling from a higher to a lower level.
Example
"Historians debated the gradual degeneration of civic institutions during the final decades of the empire."
Synonyms
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View all antonyms for degeneration• Rhymes for degeneration
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Word Origin & Etymology
Borrowed in the 15th century from Late Latin degeneratio, from the verb degenerare ('to be inferior to one's ancestors' or 'to fall from one's ancestral quality'), formed from de- ('down from') and genus ('birth, race, or kind').
Cite this Entry
Wordmom. (2026). Definition of Degeneration. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/degeneration