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Definition of pachygyria
pachygyria
/ˌpækɪˈdʒaɪriə/
pach · y · gy · ri · a
Adjective:pachygyric
pachygyria Lexical Profile
CEFR
C2
Grade
13
Tier
3
Usage
Rare
pachygyria Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
A congenital developmental disorder of the brain characterized by unusually thick and broad convolutions (gyri) of the cerebral cortex, resulting from abnormal neuronal migration during embryonic development.
Example
"The pediatric neurologist noted widespread pachygyria on the MRI, which explained the infant's severe developmental delays and early-onset seizures."
Synonyms
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Word Origin & Etymology
Derived from the Greek words 'pachys' meaning 'thick', 'gyros' meaning 'ring' or 'convolution', combined with the medical suffix '-ia' denoting a condition.
Cite this Entry
Wordmom. (2026). Definition of Pachygyria. In Wordmom Dictionary. Retrieved Oct 12, 2026, from https://wordmom.com/dictionary/pachygyria