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Definition of mitragynine
mitragynine
/mɪˈtrædʒəniːn/
mi · tra · gy · nine
mitragynine Lexical Profile
CEFR
C2
Grade
13
Tier
3
Usage
Rare
Syllables
4
mitragynine Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
An indole-based alkaloid and the principal active chemical compound found in the leaves of the kratom plant (Mitragyna speciosa), known for producing dose-dependent stimulant and opioid-like analgesic effects.
Example
"Researchers are heavily studying mitragynine to better understand its pharmacological profile and its potential as a pain management alternative."
Word Nuance & Usage
While often used interchangeably with 'kratom' in informal contexts, mitragynine refers strictly to the primary active alkaloid isolated from the plant, rather than the raw botanical material itself.
• Nearby Words
Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Mitragynine. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/mitragynine