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Definition of mitragynine
mitragynine
/mɪˈtrædʒəniːn/
mi · tra · gy · nine
mitragynine Lexical Profile
CEFR
C2
Grade
13
Tier
3
Usage
Rare
mitragynine Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
An indole-based alkaloid and the principal active chemical compound found in the leaves of the kratom plant (Mitragyna speciosa), known for producing dose-dependent stimulant and opioid-like analgesic effects.
Example
"Researchers are heavily studying mitragynine to better understand its pharmacological profile and its potential as a pain management alternative."
Word Nuance & Usage
While often used interchangeably with 'kratom' in informal contexts, mitragynine refers strictly to the primary active alkaloid isolated from the plant, rather than the raw botanical material itself.
Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Mitragynine. In Wordmom Dictionary. Retrieved Oct 16, 2026, from https://wordmom.com/dictionary/mitragynine