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Definition of antagonize

antagonize

/ænˈtæɡ.ə.naɪz/
(UK: antagonise)
an · tag · o · nize
Adverb:antagonistically
•
Adjective:antagonistic
•
Past Simple:antagonized
•
Past Participle:antagonized
•
Present Participle:antagonizing
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antagonize Lexical Profile

antagonize Game Scores & Validity

• verb

1

To cause someone to become hostile, angry, or resentful.

Example

"The mayor's controversial remarks seemed calculated to antagonize the opposition."

2

To act in opposition to or counteract the physiological effect of another substance, muscle, or force (especially in biology and pharmacology).

Example

"This specific medication is designed to antagonize the receptors responsible for the allergic reaction."

Synonyms
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Antonyms
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• Rhymes for antagonize

• Nearby Words

antagonistic
antagonistically
antagonization
antagonize
antagonizer
antalya
antananarivo

Word Origin & Etymology

Borrowed in the 17th century from Ancient Greek 'antagonizesthai' (to struggle against), formed from 'anti-' (against) and 'agon' (contest or struggle).

Cite this Entry

Wordmom. (2026). Definition of Antagonize. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/antagonize
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