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Definition of virulence
virulence
/ˈvɪrjələns/
vir · u · lence
Adverb:virulently
•Plural:virulences
•Adjective:virulent
virulence Lexical Profile
CEFR
C1
Grade
12
Tier
2
Usage
Rare
Syllables
3
virulence Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
The severity, harmfulness, or degree of pathogenicity of a disease, toxin, or microorganism.
Example
"Epidemiologists closely monitored the mutated strain to determine whether its virulence had increased."
2
Extreme bitterness, malice, or hostility in speech, writing, or attitude.
Example
"The unexpected virulence of the critic's review shocked the young playwright."
Synonyms
View all synonyms for virulence Antonyms
View all antonyms for virulence• Rhymes for virulence
• Nearby Words
Word Origin & Etymology
Borrowed in the late 16th century from Middle French or Late Latin virulentia, derived from Latin virulentus ('full of poison'), from virus ('poison, slime, or venom').
Cite this Entry
Wordmom. (2026). Definition of Virulence. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/virulence