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Definition of predisposition
predisposition
/ˌpriːdɪspəˈzɪʃ.ən/
pre · dis · po · si · tion
Plural:predispositions
•Adjective:predisposed
predisposition Lexical Profile
CEFR
C1
Grade
10
Tier
2
Usage
Top 10k
Syllables
5
predisposition Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
A liability or tendency to suffer from a particular medical condition, often due to genetic or environmental factors.
Example
"A family history of heart disease can indicate a genetic predisposition to high cholesterol."
2
An inclination or tendency to hold a particular attitude, belief, or behavioral pattern beforehand.
Example
"The mediator approached the negotiation without any predisposition toward either side's argument."
Synonyms
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View all antonyms for predisposition• Rhymes for predisposition
• Nearby Words
Word Origin & Etymology
Coined in the early 17th century from the prefix pre- ('before') and disposition, ultimately tracing back to the Latin verb disponere ('to arrange' or 'to put in order').
Cite this Entry
Wordmom. (2026). Definition of Predisposition. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/predisposition