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Definition of pox

pox

/pɑːks/
pox

Plural:poxes
•
Adjective:pocky
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pox Lexical Profile

pox Game Scores & Validity

• noun

1

Any of various contagious viral diseases characterized by skin eruptions or pustules that often leave pitted scars, such as chickenpox or smallpox.

Example

"Before modern vaccination programs, outbreaks of the pox devastated entire communities."


2

A curse, plague, or severe misfortune (used chiefly in archaic or literary imprecations such as "a pox on").

Example

"The character angrily wished a pox upon both rival families for their endless feuding."


3

Syphilis (usually preceded by "the"; now dated or historical).

Example

"In eighteenth-century medical treatises, syphilis was commonly referred to as the pox."

Synonyms
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Antonyms
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Word Nuance & Usage

Although originally the plural of "pock" (a pustule or blister), "pox" is treated as a singular noun in modern English (e.g., "a pox on your house").

• Rhymes for pox

Word Origin & Etymology

Originated in the 15th century as an altered spelling of "pocks," the plural of "pock" (meaning a pustule or blister), from Old English "pocc."

Cite this Entry


Wordmom. (2026). Definition of Pox. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/pox
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