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Definition of nucleic
nucleic
/nuːˈkliː.ɪk/
nu · cle · ic
nucleic Lexical Profile
CEFR
C1
Grade
10
Tier
2
Usage
Top 10k
Syllables
3
nucleic Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• adjective
1
Of, relating to, or derived from a cell nucleus or its genetic macromolecular components, especially in the phrase 'nucleic acid'.
Example
"Deoxyribonucleic acid is a complex nucleic macromolecule that carries the genetic instructions for all known cellular organisms."
Word Nuance & Usage
Used almost exclusively in the biochemical compound 'nucleic acid' (such as DNA and RNA); for general references to a cell nucleus or atomic nucleus, 'nuclear' is the standard adjective.
• Rhymes for nucleic
Word Origin & Etymology
Coined in the late 19th century (originally in German as 'Nukleinsäure' by Richard Altmann in 1889) from 'nuclein'—the phosphorus-rich substance first isolated from cell nuclei by Friedrich Miescher—combined with the chemical suffix '-ic'.
Cite this Entry
Wordmom. (2026). Definition of Nucleic. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/nucleic