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Definition of neuromelanin

neuromelanin

/ˌnʊroʊˈmɛlənɪn/
neu · ro · mel · a · nin
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neuromelanin Lexical Profile

neuromelanin Game Scores & Validity

• noun

1

A dark, insoluble granular pigment produced in specific populations of catecholaminergic neurons in the brain, particularly within the substantia nigra and locus coeruleus.

Example

"The progressive loss of neuromelanin-containing neurons in the substantia nigra is a major pathological hallmark of Parkinson's disease."

Synonyms
View all synonyms for neuromelanin

• Rhymes for neuromelanin

• Nearby Words

neurologically
neurologist
neurology
neuromelanin
neuron
neuroprotective
neuroscientist

Word Origin & Etymology

Coined in the mid-20th century by combining the prefix 'neuro-' (from Greek 'neuron', meaning nerve) and 'melanin' (from Greek 'melas', meaning black), denoting the specific dark pigment present in mammalian brains.

Usage Trend

Historical frequency of usage in published text.

180019102020
Data source: Google Books Ngram Viewer

Cite this Entry

Wordmom. (2026). Definition of Neuromelanin. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/neuromelanin
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