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Definition of mono

mono

/ˈmɑːnoʊ/
mo · no

Plural:monos
•
Adjective:mono
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mono Lexical Profile

mono Game Scores & Validity

• noun

1

North American An acute infectious disease, primarily caused by the Epstein-Barr virus, characterized by fever, swollen lymph nodes, and extreme fatigue; a colloquial clipping of infectious mononucleosis.

Example

"He missed three weeks of high school after coming down with a severe case of mono."


2

Sound reproduction that uses a single audio transmission channel, as opposed to stereophonic sound.

Example

"Many vintage music purists prefer listening to early Beatles albums mixed in mono."

Word Nuance & Usage

When referring to the illness, 'mono' is primarily a North American colloquialism; in British English, the condition is commonly known as 'glandular fever'.

• Rhymes for mono

Word Origin & Etymology

A clipping of 'monophonic' (in audio contexts) or 'mononucleosis' (in medical contexts), ultimately derived from the Greek 'monos', meaning 'single' or 'alone'.

Cite this Entry


Wordmom. (2026). Definition of Mono. In Wordmom Dictionary. Retrieved Oct 14, 2026, from https://wordmom.com/dictionary/mono
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