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Definition of metastasize
metastasize
/məˈtæs.tə.saɪz/
(UK: metastasise)
me · tas · ta · size
Adverb:metastatically
•Adjective:metastatic
•Past Simple:metastasized
•Past Participle:metastasized
•Present Participle:metastasizing
metastasize Lexical Profile
CEFR
C2
Grade
12
Tier
2
Usage
Rare
Syllables
4
metastasize Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• verb
1
To spread to other sites in the body via the bloodstream or lymphatic system (of a cancer or disease-producing agency).
Example
"Early detection is crucial so Doctors can treat the tumor before the malignant cells metastasize to the lymph nodes."
2
To spread, multiply, or develop rapidly in a harmful, destructive, or uncontrollable way (of a problem, crisis, or harmful phenomenon).
Example
"Left unaddressed by regulators, the localized banking crisis began to metastasize into a global economic recession."
Synonyms
View all synonyms for metastasize Antonyms
View all antonyms for metastasize• Rhymes for metastasize
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Word Origin & Etymology
Coined in the late 19th century from the noun 'metastasis', which derives from Ancient Greek 'metastasis' meaning 'removal' or 'change', formed from 'meta-' (change) and 'histemi' (to place or cause to stand).
Cite this Entry
Wordmom. (2026). Definition of Metastasize. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/metastasize