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Definition of mdma
mdma
/ˌɛm.diː.ɛmˈeɪ/
mdma Lexical Profile
CEFR
C1
Grade
12
Tier
2
Usage
Rare
Syllables
4
• noun
1
A synthetic psychoactive substance (3,4-methylenedioxymethamphetamine) with both stimulant and hallucinogenic properties, known for producing feelings of euphoria, heightened sensory perception, and emotional empathy.
Example
"Clinical researchers have been investigating whether controlled doses of MDMA can assist in psychotherapy for severe post-traumatic stress disorder."
Synonyms
View all synonyms for mdma• Rhymes for mdma
Word Origin & Etymology
An initialism of its systematic chemical name, 3,4-methylenedioxymethamphetamine, first synthesized in 1912 by the German chemist Anton Köllisch at Merck.
Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Mdma. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/mdma