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Definition of malignancy
malignancy
/məˈlɪɡ.nən.si/
ma · lig · nan · cy
Adverb:malignantly
•Plural:malignancies
•Adjective:malignant
malignancy Lexical Profile
CEFR
C1
Grade
11
Tier
2
Usage
Top 10k
Syllables
4
malignancy Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
The state or presence of a cancerous growth, or a cancerous tumor itself that tends to invade surrounding tissue and metastasize.
Example
"Early screening allowed the oncologist to detect the malignancy before it could spread to other organs."
2
The quality or state of being intensely malevolent, spiteful, or disposed to cause harm and suffering.
Example
"The sheer malignancy of the rumor campaign damaged the reputation of several innocent colleagues."
Synonyms
View all synonyms for malignancy Antonyms
View all antonyms for malignancy• Rhymes for malignancy
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Word Origin & Etymology
Derived from the Late Latin verb 'malignare' (to act maliciously or contrive wickedly), which itself combines 'malus' (bad) and the root 'gignere' (to beget or produce), literally meaning 'ill-disposed by nature.'
Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Malignancy. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/malignancy