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Definition of mainline

mainline

/ˈmeɪn.laɪn/
main · line

Plural:mainlines
•
Past Simple:mainlined
•
Past Participle:mainlined
•
Present Participle:mainlining
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mainline Lexical Profile

mainline Game Scores & Validity

• adjective

1

Belonging to or characteristic of a principal, established, or traditional group, movement, or religious denomination.

Example

"Several mainline Protestant denominations collaborated on the community charity initiative."


2

Relating to or operating along a primary railway line, highway, or utility route.

Example

"The transit authority announced major upgrades to all mainline stations before the winter season."

Synonyms
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Antonyms
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• noun

1

A principal railway track, road, or utility conduit through which major traffic or supply flows.

Example

"Freight trains were delayed for hours after a fallen tree blocked the mainline."


2

In corded ropes or fishing gear, the principal line to which secondary lines, hooks, or leaders are attached.

Example

"The angler carefully tied the fluorocarbon leader onto the braided mainline."

Synonyms
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Antonyms
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• verb

1

To inject a narcotic drug directly into a principal vein, or figuratively to consume something rapidly and in large quantities.

Example

"During finals week, the exhausted students joked that they were mainlining espresso just to stay awake."

Word Origin & Etymology

Formed in the 19th century as a compound of 'main' and 'line', originally designating the principal track of a railway system before acquiring its slang sense of a major vein in the 1930s.

Cite this Entry


Wordmom. (2026). Definition of Mainline. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/mainline
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