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Definition of isthmus
isthmus
/ˈɪs.məs/
isth · mus
Plural:isthmuses
•Adjective:isthmian
isthmus Lexical Profile
CEFR
B2
Grade
6
Tier
3
Usage
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isthmus Game Scores & Validity
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• noun
1
A relatively narrow strip of land, bordered on both sides by water, that connects two larger landmasses.
Example
"The Isthmus of Panama connects North and South America while separating the Atlantic and Pacific Oceans."
2
A narrow organ, passage, or piece of tissue connecting two larger parts of an organ or anatomical structure, such as the lateral lobes of the thyroid gland.
Example
"The surgeon carefully examined the isthmus of the thyroid gland to ensure there were no irregular nodules."
Synonyms
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View all antonyms for isthmusWord Origin & Etymology
From Latin 'isthmus', derived from ancient Greek 'isthmós' meaning 'neck' or 'narrow passage'.
Cite this Entry
Wordmom. (2026). Definition of Isthmus. In Wordmom Dictionary. Retrieved Oct 12, 2026, from https://wordmom.com/dictionary/isthmus