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Definition of inoculation

inoculation

/ɪˌnɑːkjəˈleɪʃən/
in · oc · u · la · tion

Plural:inoculations
•
Adjective:inoculative
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inoculation Lexical Profile

inoculation Game Scores & Validity

• noun

1

The action or process of introducing an antigenic substance or vaccine into the body to stimulate the production of antibodies and provide immunity against a specific disease.

Example

"All international travelers entering the region must present proof of a yellow fever inoculation."


2

In microbiology, the introduction of microorganisms, cells, or infectious material into a culture medium such as an agar plate or broth to cultivate them.

Example

"The lab technician sterilized the wire loop over a Bunsen burner prior to the inoculation of the nutrient broth."


3

The act of protecting or fortifying someone's mind against harmful ideas, misinformation, or undesirable influences through preemptive exposure to weakened arguments.

Example

"Teaching students critical thinking skills serves as an effective inoculation against online propaganda."

Synonyms
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Antonyms
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Word Nuance & Usage

'Inoculation' is often confused with 'vaccination' and 'immunization'; historically, inoculation referred specifically to introducing live smallpox matter (variolation), whereas today it denotes the physical act of introducing a vaccine or antigen, while 'immunization' refers to the resulting biological process of developing immunity.

• Rhymes for inoculation

Word Origin & Etymology

From Late Middle English, derived from the Latin 'inoculatio', meaning 'an engrafting of buds' (from 'in-' meaning 'into' + 'oculus' meaning 'eye' or 'bud'). Originally a horticultural term for grafting a bud from one plant into another, it was adopted in the early 18th century for the medical practice of introducing smallpox matter into the skin.

Cite this Entry


Wordmom. (2026). Definition of Inoculation. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/inoculation
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