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Definition of exacerbation
exacerbation
/ɪɡˌzæs.ərˈbeɪ.ʃən/
ex · ac · er · ba · tion
Plural:exacerbations
•Adjective:exacerbated
exacerbation Lexical Profile
CEFR
C1
Grade
12
Tier
2
Usage
Top 10k
Syllables
5
exacerbation Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
The act or process of making a problem, bad situation, or negative feeling worse; an increase in severity.
Example
"The prolonged drought led to a severe exacerbation of food shortages across the region."
2
An acute increase in the severity of a chronic disease, medical condition, or its symptoms.
Example
"Exposure to cold air and pollen can trigger an acute exacerbation of asthma in sensitive patients."
Synonyms
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View all antonyms for exacerbation• Rhymes for exacerbation
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Word Origin & Etymology
Borrowed in the mid-17th century from Late Latin exacerbatio, from the verb exacerbare ('to irritate, provoke, or make harsh'), formed from ex- ('thoroughly') and acerbus ('bitter, sour, or harsh').
Cite this Entry
Wordmom. (2026). Definition of Exacerbation. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/exacerbation