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Definition of disease

disease

/dɪˈziːz/
dis · ease

Plural:diseases
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Adjective:diseased
•
Past Simple:diseased
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Past Participle:diseased
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Present Participle:diseasing
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disease Lexical Profile

disease Game Scores & Validity

• noun

1

A disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or affects a specific location and is not simply a direct result of physical injury.

Example

"Vaccination programs have dramatically reduced the spread of infectious diseases worldwide."


2

A harmful, corrupting, or destructive condition or habit within a society, institution, or group.

Example

"The historian argued that systemic corruption was a disease that slowly weakened the empire from within."

Synonyms
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Antonyms
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• verb

1

To make ill or infect with a pathological condition, or to corrupt morally (mostly used in the past participle).

Example

"The arborist removed the branches that had been diseased by the invasive fungus."

Synonyms
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Word Nuance & Usage

In medical contexts, 'disease' refers to an objective pathological process with identifiable signs or causes, whereas 'illness' refers to a patient's subjective experience of feeling unwell.

• Rhymes for disease

Word Origin & Etymology

Borrowed from Anglo-Norman 'desease' (Old French 'desaise'), combining 'des-' (expressing reversal or lack) and 'aise' ('ease, comfort'), originally meaning a general lack of comfort or convenience before narrowing to medical pathology.

Cite this Entry


Wordmom. (2026). Definition of Disease. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/disease
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