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Definition of diego
diego
/diˈeɪ.ɡoʊ/
di · e · go
Plural:Diegos
diego Lexical Profile
CEFR
B1
Grade
4
Tier
2
Usage
Top 10k
Syllables
3
• noun
1
A masculine given name of Spanish origin, traditionally corresponding to the English name James.
Example
"They decided to name their newborn son Diego in honor of his grandfather."
2
An inherited blood group system and red blood cell antigen complex defined by variations on the band 3 glycoprotein, often studied in transfusion medicine and population genetics.
Example
"The hematology lab screened the donor's blood sample for rare antibodies in the Diego blood group system."
• Rhymes for diego
Word Origin & Etymology
Borrowed from the Spanish given name Diego, which evolved from Medieval Spanish Sant Yago (Saint James) through false word division into San Tiago and subsequently Diego.
Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Diego. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/diego