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Definition of des
des
/ˌdiːˌiːˈɛs/
des
Plural:des
des Lexical Profile
CEFR
C2
Grade
13
Tier
2
Usage
Rare
Syllables
3
des Game Scores & Validity
Scrabble US
Scrabble UK
WWF
Wordle Guess
• noun
1
A synthetic nonsteroidal estrogen (diethylstilbestrol) formerly prescribed to prevent miscarriages and treat hormone-related conditions, before being largely discontinued due to adverse health effects.
Example
"Medical researchers studied the long-term health outcomes of patients who had been exposed to DES before birth."
2
An early symmetric-key block cipher algorithm (Data Encryption Standard) formerly used as a federal standard for encrypting electronic data.
Example
"Modern cryptographic systems have replaced DES with stronger algorithms like AES to protect sensitive information."
Synonyms
View all synonyms for des• Rhymes for des
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Usage Trend
Historical frequency of usage in published text.
180019102020
Data source: Google Books Ngram Viewer
Cite this Entry
Wordmom. (2026). Definition of Des. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/des