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Definition of antihistamine

antihistamine

/ˌæn.tiˈhɪs.tə.miːn/
an · ti · his · ta · mine
Plural:antihistamines
•
Adjective:antihistaminic
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antihistamine Lexical Profile

antihistamine Game Scores & Validity

• noun

1

A pharmaceutical drug or other compound that inhibits the physiological effects of histamine, used especially in the treatment of allergies, hay fever, and colds.

Example

"She took an over-the-counter antihistamine as soon as her eyes started itching from the pollen."

• adjective

1

Relating to, containing, or acting as a substance that counteracts the physiological effects of histamine.

Example

"The pharmacist recommended an antihistamine nasal spray to relieve her seasonal congestion."

Synonyms
View all synonyms for antihistamine

• Rhymes for antihistamine

• Nearby Words

antihelix
antihero
antiheroine
antihistamine
antihomosexual
antihunger
antihunter

Word Origin & Etymology

Coined in the 1930s from the prefix 'anti-' (against) and 'histamine', which itself derives from Ancient Greek 'histos' (tissue or web) combined with 'amine'.

Cite this Entry

Wordmom. (2026). Definition of Antihistamine. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/antihistamine
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