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Definition of antidepressant

antidepressant

/ˌæn.ti.dɪˈprɛs.ənt/
an · ti · de · pres · sant
Plural:antidepressants
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antidepressant Lexical Profile

antidepressant Game Scores & Validity

• noun

1

A pharmaceutical drug prescribed to alleviate or prevent clinical depression, anxiety, and related mood disorders by regulating neurotransmitters in the brain.

Example

"The psychiatrist prescribed a low-dose antidepressant alongside weekly cognitive behavioral therapy."

Synonyms
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Antonyms
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• adjective

1

Serving to prevent, alleviate, or treat clinical depression or related mood disorders.

Example

"Regular physical exercise has well-documented antidepressant effects on the human brain."

Synonyms
View all synonyms for antidepressant
Antonyms
View all antonyms for antidepressant

• Rhymes for antidepressant

• Nearby Words

anticyclone
antidandruff
antidemocratic
antidepressant
antidiarrheal
antidote
antidrug

Word Origin & Etymology

Coined in the early 1950s by combining the Greek-derived prefix 'anti-' (against) with 'depressant', coinciding with the clinical discovery of the first psychiatric medications used to treat clinical depression.

Cite this Entry

Wordmom. (2026). Definition of Antidepressant. In Wordmom Dictionary. Retrieved Nov 5, 2026, from https://wordmom.com/dictionary/antidepressant
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